Generic Viagra

Generic Viagra

Sildenafil is a drug of the form P450 -1A2, 2C19, 2E1, 2C9, 2D6 and 3A4. It will not affect the work of the presented enzymes, if it will be used in those doses that are intended.

If the drug itself is used, the property of nitrates becomes much more. Such a reaction can appear not only when the drug is taken for a long time, but also when it was prescribed for acute testimony. Builders of nitric oxide and nitrates can not be used with sildenafil. This is contraindicated.

It is worth to be cautious and people who have prostatic hyperplasia and apply α-adrenoblocker doxazosin. In combination with sildenafil, different pressure will begin to decrease. There were also situations when the patient began to develop symptomatic postural hypotension. These are very rare cases. But the person started to feel dizzy, and sometimes he lost consciousness. It is worth paying attention to the behavior of the organism individually. After all, a very sensitive patient who takes alpha-adrenoblockers at the same time can get symptomatic hypotension if he uses sildenafil. This consequence is very undesirable.

A study was also conducted on the reaction of the body to the combination of sildenafil and tolbunamide, warfarin. Subsequently, no changes were identified.

  • The preparation will not work on the pharmacokinetics of saquinavir or ritonavir. The only condition is only the constant presence of them in the blood. If a person takes acetylsalicylic acid, then 50 mg of sildenafil will not have a negative effect on the action of the drug, bleeding will not increase its time.
  • There were also studies on the combination of the drug with alcohol. It has been shown that the hypotensive effect does not increase, but it is worthwhile to see that there is not a lot of alcohol in the blood, the optimal index is not more than 0.08%.

Lactation and pregnancy

  • This drug was not created for use by women, so it is not intended for them.

Side effects

Side effects from sildenafil do not manifest themselves brightly. Usually the drug has a weak effect on the body. It is very rare for a person to have any consequences from taking, most likely this happens in those to whom the drug was contraindicated. Side effects are the same as overdose. Do not increase the amount of sildenafil, because it will not lead to the desired consequences. There are such unpleasant effects:

1. The state of the body is significantly deteriorating. A person reacts badly to light, there is pain in the chest or abdomen, chills, face swells, it can lead to shock.

2. A person develops allergies, and they can manifest themselves in different ways. Some have a skin rash, some have Lyell’s syndrome or Steven-Johnson syndrome.

3. The central nervous system is broken from overdose. Subsequently there will be a sleeplessness or on the contrary drowsiness. A person suddenly falls depressed. There are also worse cases when hypoesthesia, ataxia, tremor, nervopathy, stroke develop, reflexes noticeably decrease, convulsions appear.

4. Violated and the cardiovascular system. In this case, tachycardia appears, BP decreases or increases, atrial fibrillation, unstable angina. In the worst cases, there is a heart attack, a thrombosis of the vessels that are in the brain, cardiomyopathy and even death, which occurs very quickly and unexpectedly.

5. The respiratory function fails. As a result, there may be bleeding through the nose, asthma or shortness of breath, pharyngitis or laryngitis, the appearance of cough and sputum, which is secreted.

6. The gastrointestinal tract ceases to function normally. In the mouth it becomes dry, there is vomiting, nausea, gastritis, gastroenteritis, gingivitis, stomatitis and other can appear.

7. The organs of vision change markedly: blush, hurt, lachrymation is disturbed, retinal vessels are affected. In some cases, cataracts, conjunctivitis and visual field defects were observed.

8. The hearing is broken. A person sometimes ceases to hear anything, or there is a severe pain in the ears.

9. The metabolism is fundamentally disrupted, and the process of nutrition does not occur normally. A person may experience severe thirst, he has a hypoglycemic reaction, hypernatremia and other diseases.

10. It can be bad for the musculoskeletal system.

11. A person can develop leukopenia or anemia, that is, the circulatory system normally stops working.

12. There are changes and abnormalities that are associated with the skin.

13. Disorders of the genitourinary system, up to incontinence.

14. As a result, too much erection may appear.

 How to store the drug?

It is better that the drug lay in a place where it is dark and there is no increased humidity, the temperature is at the same time the most optimal average, but not more than 25 degrees. It should be ensured that children can not get to the facility, because on their health it can have deplorable consequences.